Next Generation Endoscopic Ultrasound Core Needle Biopsy Device
EndoDrill® GI is the world’s first US FDA-cleared and EU CE-approved electric-driven core needle biopsy device for endoscopic ultrasound (EUS-CNB). EndoDrill® consists of a sterile core needle biopsy instrument with an associated drive system.
Unlike conventional manual needle instruments, EndoDrill® features a motorized, rotating drill-tip cylinder. This design enables deep, precise tissue sampling. One or more solid core biopsies are extracted, providing the tissue architecture required for complete histological diagnosis, staging, and genetic analysis.
Published clinical studies and case series from the U.S. and Europe using EndoDrill® GI for tissue acquisition in multiple GI indications (e.g., stomach, pancreas, and liver) show very promising results. Although the studies are limited in size, they consistently report a high diagnostic yield, often achieved already after the first needle pass.
1. Swahn F, Glavas R, Hultin L, Wickbom M. The advent of the first electric-driven EUS-guided 17G core needle biopsy – A pilot study on subepithelial lesions. Scand J Gastroenterol. 2024;59(7):852–858.
2. Mendoza Ladd A, Alsamman A, Meiklejohn K, et al. Initial experience with a new endoscopic ultrasound electric core needle biopsy device: A case series. Endosc Int Open. 2024.
3. Oliver M, Kabir K, Ognjanovski E, Barawi M. Endoscopic ultrasound-guided motorized fine needle aspiration (“EndoDrill”) liver biopsy: Case vignette. Abstract, 4th Annual Michigan GI Society Conference, 2025.
2. Mendoza Ladd A, Alsamman A, Meiklejohn K, et al. Initial experience with a new endoscopic ultrasound electric core needle biopsy device: A case series. Endosc Int Open. 2024.
4. Mendoza Ladd A, Pham KDC, Pavic T, Glavas R, Swahn F. EndoDrill® core needle biopsy: Preliminary multicenter experience. Endoscopy. 2025;57(Suppl 2):182–183.
Its flexible design allows for sampling at steep angulations, enabling high-quality tissue acquisition from hard-to-reach tumors that are often difficult to access with conventional, more rigid biopsy needles.
Experience unparalleled clarity with EndoDrill® GI’s advanced EUS-guided core drilling. The system provides real-time visibility during biopsies, allowing clinicians to precisely control the depth and angle of tissue sampling under ultrasound guidance. This design significantly enhances procedural accuracy and confidence.
| Article Name | Article Number | Order Quantity | Needle Size (Gauge) | Adjustable Needle Length (cm)* | Minimum Accessory Channel (mm)* |
|---|---|---|---|---|---|
| EndoDrill® GI Biopsy Instrument | 13001 | 3 | 17 | 0-6 | 2.8 |
| EndoDrill® GI Biopsy Instrument | 13002 | 5 | 17 | 0-6 | 2.8 |
| EndoDrill® Drive System | 3000-01 | 1 | Complete reusable system including motor unit, power supply cable, foot pedal and drive cable | ||
EndoDrill® GI is intended to be used with an ultrasound endoscope for ultrasonically guided fine needle sampling of submucosal- and extramural lesions within gastrointestinal tract, i.e. esophagus, mediastinal masses, stomach, pancreas, liver, small- and large intestines, lymph nodes and perirectal masses. This device is for diagnostic purposes only.
For inquiries or to place an order please contact us:
Manufacturer: 
BiBBInstruments AB Medicon Village | SE-223 81 Lund, Sweden | www.bibbinstruments.com
© 2025 BiBBInstruments AB, All right reserved. Unless otherwise indicated, all marks with® are registered trademarks owned by BiBBInstruments.
Visit BiBBInstruments website to learn more details about the product and clinical data:
